despair of
1．be without hope of 绝望；丧失信心
Don't despair of success；where there is a will，there is a way．别对成功悲观失望，有志者事竟成。
He despaired of winning the game．他丧失了赢得这场比赛的信心。
The patient's life was despaired of．这个病人没有救活的希望。
2．feel very anxious about 非常担忧
She despairs of her son．她为她儿子担心。